蔡瑾

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2025-03-21


蔡瑾.jpg


姓名:蔡瑾

职称:副教授

联系方式:13453439509

介绍:

 蔡瑾,山西太原人,理学博士,副教授,硕士研究生导师,“三晋英才”青年优秀人才,山西省微生物学会理事,山西省植物学会会员。现从事中药植物资源利用、药物与膜互作机制、靶向性载药新型纳米材料、中药源智能化纳米型食品包装材料、药用植物先导化合物发掘及改造等研究。主持国家自然科学基金青年基金项目1项,山西省自然科学研究项目2项,山西省教育厅高等学校科技创新项目1项,中央提升人才事业启动经费1项,横向课题2项,参与国家基金面上基金2项。已在国内外核心期刊上发表学术论文30余篇,授权国家发明专利5项。

学习与工作经历

2017/12 - 至今,山西大学,应用化学研究所,副教授

2014/9 - 2017/11,山西大学,应用化学研究所,讲师

2009/9 - 2014/7,山西大学,生命科学学院,博士

2006/9 - 2009/7,山西大学,生命科学学院,硕士

2001/9 - 2005/7,山西农业大学,农学院,学士

主要科研项目

[1] 红蓼抗马铃薯环腐病菌天然先导化合物的发掘及其基于脂质体模型的作用方式研究,国家自然科学基金青年基金项目(No.31601677),起止时间:2017.01-2019.12,20万元,主持

[2] 抗番茄溃疡病菌红蓼活性衍生物的设计合成及与DNA的互作关系研究,山西省自然科学研究面上项目(No.20210302123451),起止时间:2022.1-2024.12,9万元,主持

[3] 红蓼活性物质抑制马铃薯环腐病菌DNA复制的机理研究,山西省应用基础研究面上青年基金项目(No.201701D221179),起止时间:2017.07-2019.12,2万,主持

[4] 红蓼活性物质抑制番茄溃疡病菌DNA复制的机理研究,山西省高等学校科技创新项目(No.2016117),起止时间:2016.04-2018.04,3万元,主持。

[5] 中央提升蔡瑾人才事业启动经费,山西大学科研启动经(No.204545003),起止时间:2014.1-2018.12,14万,主持

[6]Angiopep-2修饰的新型pH响应纳米囊泡的设计与合成,横向经费 (No.02040124060070 ),起止时间:2024.05-2025.05,5万元,主持

[7] 阿胶糖胺聚糖的提取、鉴定及含量测定,横向经费 (No.02040124040038 ),2024.4-2024.10,5万元,主持

代表性论文

[1] Jin Cai*, Shiqin Wang, Qi Wang. Antibacterial activity of dihydroquercetin separated from Fructus Polygoni orientalis against Clavibacter michiganensis subsp. sepedonicus via damaging cell membrane. Foods, 2024, 13: 23.(二区)

[2] Jin Cai*, Dongmei Yang, Qi Wang. Preparation and characterization of chitosan nanoparticles loaded with Athyrium sinense essential oil with antibacterial properties against Pectobacterium carotovorum subsp. carotovorum . Industrial Crops & Products, 2023, 195: 116382.(一区,TOP)

[3] Jin Cai*, Shiqin Wang, Yichen Gao, Qi Wang. Antibacterial activity and mechanism of Polygonum orientale L. essential oil against Pectobacterium carotovorum subsp. carotovorum . Foods, 2022, 11: 1585.(二区)

[4] Jin Cai*, Beibei Du, Le Kang, Junjun Guo. Antimicrobial compounds from Athyrium sinense damage the cell membrane of Clavibacter michiganensis subsp. sepedonicus. Journal of Applied Botany and Food Quality, 2020, 93: 76–83.(四区)

[5] Jin Cai*, Dongmei Yang, Jing Zhang, Junjun Guo, Lijun Jiang. Evaluation of bio-guided fraction from Laminaria japonica as a natural food preservative based on antimicrobial activity. Journal of Food Measurement and Characterization, 2020, 14: 735–748.(三区)

[6] Jin Cai*, Yichen Gao, Mengliang Wang, Jing Zhang, Yongbin Zhang, Qi Wang, Jiquan Liu. Antibacterial activity of Polygonum orientale extracts against Clavibacter michiganensis subsp. michiganensis, the agent of bacterial canker of tomato disease. Brazilian Archives of Biology and Technology, 2019, 62: e19180021.(四区)

[7] Jin Cai, Mengliang Wang*, Xiaoxia Zhao, Yanyan Zhang, Xin Yuan. Antimicrobial activity of Laminaria japonica extracts against bacterial canker of tomato disease agent Clavibacter michiganensis subsp. michiganensis. Journal of Applied Botany and Food Quality, 2017, 90: 183–190.(四区)

[8] Jin Cai, Jia Feng, Shulian Xie*. Inhibitory activity of Athyrium sinense extracts against Clavibater michiganense subsp. sepedonicum. Journal of Applied Botany and Food Quality, 2015, 88: 314–321. (四区)

[9] Jin Cai, Jia Feng, Feipeng Wang, Qiufeng Xu, Shulian Xie*. Antibacterial activity of petroleum ether fraction from Laminaria japonica extracts against Clavibacter michiganensis subsp. sepedonicus. European Journal of Plant Pathology, 2014, 140: 291–300. (三区)

[10] Jin Cai, Jia Feng, Shulian Xie*, Feipeng Wang, Qiufeng Xu. Laminaria japonica extract, an inhibitor of Clavibater michiganense subsp. sepedonicum. Plos One, 2014, 9(4): e94329.(三区)

[11] Jin Cai, Shulian Xie*, Jia Feng, Feipeng Wang, Qiufeng Xu. Protective effect of polygonum orientale L. extracts against Clavibater michiganense subsp. sepedonicum, the causal agent of bacterial ring rot of potato. Plos One, 2013, 8(7): e68480.(三区)

[12] Qi Wang*, Jiaqin Liu, Jin Ca, Sanhong Fan. Functional characteristics of lactic acid bacteria In Vitro isolated from spontaneously fermented sour porridge with broomcorn millet in northwestern Shanxi province of China. Foods, 2022,11, 2353

[13] Jiquan Liu*, Jin Cai, Runli He, Xichun Zhang. Influences of Funneliformis mosseae on the photosynthetic parameters and active secondary metabolites contents of Astragalus membranaceus and Astragalus membranaceus var. mongholicus. ScienceAsia, 2019, 45: 324–331.

[14] Kai Wang, Jin Cai, Shulian Xie*, Jia Feng, Ting Wang. Phytoremediation of phenol using Polygonum orientale and its antioxidative response. Archives of Environmental Protection, 2015, 41(3): 39-46.

[15] Kai Wang, Jin Cai, Jia Feng, Shulian Xie*. Phytoremediation of phenol using Polygonum orientale, including optimized conditions. Environmental Monitoring and Assessment, 2014, 14(15): 1671-1815.

[16] Jinhua Zhang, Jia Feng, Jin Cai, Ying Shi, Junping Lv, Qi Liu, Shulian Xie*. Toxic effects of 1,4-Dichlorobenzene on Chlorella pyrenoidosa: cell morphology, antioxidant system, and membrane permeability. Fresenius Environmental Bulletin, 2017, 26: 1932-1939.

[17] Jinhua Zhang, Jie Wang, Jia Feng, Junping Lv, Jin Cai, Qi Liu, Shulian Xie*. Toxic effects of 1, 4-Dichlorobenzene on Photosynthesis in Chlorella pyrenoidosa. Environmental Monitoring and Assessment, 2016, 188(9): 526.

[18] Jiquan Liu, Shulian Xie*, Jia Feng, Jin Cai. Effects of chloroform extract of Dryopteris crassirhizoma on the ultramicroscopic structure of Meloidogyne incognita. The Scientific World Journal, 2013, 313482.

[19] Jiquan Liu, Shulian Xie*, Jia Feng, Jin Cai. Protective effect of Dryopteris crassirhizoma extracts in the control of the root-knot nematode Meloidogyne incognita. Journal of Plant Diseases and Protection, 2013, 120: 34-40.

[20] 蔡瑾*, 闫然, 王梦亮, 王琪. 二氢槲皮素对大肠杆菌的抑菌作用机理. 食品科学, 2023, 44(19):18–26.

[21] 蔡瑾, 冯佳, 王凯, 谢树莲*, 王飞鹏. 海带对密执安棒形杆菌环腐亚种的抑菌活性及其加工制剂的研究. 科学技术与工程, 2014, 14(15): 1671–1815.

[22] 渠红, 王梦亮, 闫然, 王琪, 蔡瑾*. 中华蹄盖蕨挥发油对番茄溃疡病菌的抑菌效果及机理研究. 中国农学通报, 2023, 39(31): 139–146.

[23] 闫然,秦雪梅,王琪,蔡瑾*,抗番茄溃疡病菌菱角壳活性物质提取条件优化及抑菌活性研究. 食品工业, 2022, 43(12): 65-69.

[24] 杜贝贝, 谢树莲, 王梦亮, 蔡瑾*. 海带石油醚相活性物质对番茄溃疡病菌的抑菌机理. 中国农学通报, 2020, 36(33): 127–133.

[25] 杜贝贝, 谢树莲, 王梦亮, 高以宸, 蔡瑾*. 中华蹄盖蕨抗番茄溃疡病菌活性物质提取工艺优化及其抑菌作用研究. 食品工业科技, 2019, 40(24): 1–7.

[26] 高以宸, 蔡瑾*, 王梦亮, 史晓晶. 红蓼挥发油杀菌剂对马铃薯环腐病的防治效果. 山西农业科学, 2019, 47(12): 2185–2188.

[27] 高以宸, 谢树莲, 王梦亮, 任璐, 蔡瑾*, 赵雯艳. 红蓼挥发油植物源杀菌剂的研制及其对三种细菌性植物病原菌的抑菌作用. 科学技术与工程, 2019, 19(31): 93–107.

[28] 刘晓峰, 石玉星, 赵晓军, 蔡瑾, 张宝俊, 任璐*. 曼陀罗内生细菌 MY1 对谷子抗病促生特性的影响. 山西农业科学, 2019: 47(9): 1622–1626.

[29] 王凯, 冯佳, 蔡瑾, 谢树莲*. 两种植物对水体中苯酚胁迫的响应. 山西大学学报, 2014, 37(4): 630-636.

[30] 王凯, 栗霞, 蔡瑾, 冯佳, 谢树莲*. 六种水生植物对焦化废水中氨氮和COD的去除作用研究. 科技导报, 2012, 30: 28-29.

[31] 刘计权, 谢树莲*, 蔡瑾, 尹晓琴, 苏志兰. UV和HPLC测定草问荆总黄酮及山柰素含量. 山西大学学报, 2011, 34(3): 480-484.

[32] 刘计权, 谢树莲*, 蔡瑾, 尹晓琴. 林问荆山柰素的薄层鉴别及含量测定. 山西医药杂志, 2011, (3): 219-221.

授权专利

[1] 蔡瑾, 杨冬梅, 王梦亮. 中华蹄盖蕨挥发油壳聚糖纳米粒及其制备方法和应用. 授权公告日: 2023.9.22. 专利号: ZL202111560893.1.

[2] 蔡瑾, 杜贝贝. 抗马铃薯环腐病菌的槲皮素衍生物及其合成方法和应用. 授权公告日: 2023.3.10. 专利号: ZL202110365374.3.

[3] 蔡瑾, 高以宸, 张静, 王梦亮. 一种抗白菜软腐病菌的植物源杀菌剂. 授权公告日: 2021.3.30. 专利号:ZL 201910038810.9.

[4] 蔡瑾, 张静, 王梦亮. 一种防治番茄溃疡病菌的植物源杀菌剂. 授权公告日: 2021. 2. 2. 专利号:ZL 201910620797.8.

[5] 蔡瑾, 谢树莲, 冯佳, 李博, 王飞鹏. 一种防治马铃薯环腐病的植物源农药及其制备方法. 授权公告日: 2014. 6.18. 专利号: ZL201310184445.5.

[6] 张猛, 谢树莲, 石瑛, 蔡瑾, 冯佳, 刘晓玲. 一种轮藻提取物和含有轮藻提取物的洗浴用品. 授权时间: 2010.6.2, 专利号: ZL 200810054721.5 .